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KMID : 1161420230260040262
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Journal of Medicinal Food
2023 Volume.26 No. 4 p.262 ~ p.269
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Efficacy and Tolerability of Ich Nieu Khang Dietary Supplement for Overactive Bladder
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Hoan M. Vu
Van T. H. Tran
Huy Q. Hoang
Bo Han
Ba X. Hoang
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Abstract
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This study aims to assess the effectiveness and safety of plant-derived food supplement Ich Nieu Khang (INK) as a dietary supplement for overactive bladder (OAB) symptoms. A total of 50 patients 18?80 years of age with the diagnosis and symptoms of the OAB were enrolled in the study and followed up for 30 days. The INK treatment efficacy, in terms of changes in nocturnal and day-time urination frequency, urination incontinence episodes, level of OAB symptoms according to Homma's OABSS scale, sleep quality according to Pittsburg Sleep Quality Index (PSQI), and possible side effects of the INK phytotherapy, was evaluated. INK significantly improved all OAB symptoms scores with a reduction of average nocturia from 4.06?±?1.53 to 1.14?±?0.94, the daily average urination urgency from 7.67?±?5.00 to 5. 82?±?3.70, the daily average frequency of urination from 9.96?±?4.04 to 8.00?±?3.70, weekly average incontinence of urination from 0.92?±?1.56 to 0.60?±?1.02, and OABSS Homma's score decreased from 9.31?±?1.44 to 6.8?±?2.21. INK phytotherapy also resulted in sleep quality improvement by PSQI score decreasing from 13.11?±?1.33 to 10.54?±?2.21. There were no adverse effects and abnormalities in paraclinical parameters with INK therapy. The results of our study suggest that INK dietary supplement is effective and safe phytotherapy for patients with primary OAB symptoms within 30 days of treatment. Larger control clinical trials are warranted to confirm our findings and promote wider use of INK for OAB and possible other age-related urination disorders.
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KEYWORD
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food supplement, incontinence, nocturia, OAB, overactive bladder, phytotherapy
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